This is I like to call the PANIC ATTACK GENE! ❌😱
This is one of the genes associated with OVERMETHYLATION
COMT is an enzyme that breaks down a class of neurotransmitters called catecholamines. These include: Dopamine, Norepinephrine & Epinephrine (Adrenaline). COMT deactivates catecholamines by introducing a methyl group into their structure via S-adenosyl methionine. In simple words, people that have sluggish/slow COMT have a tendency to make these Dopamine and Norepinephrine at a normal rate but DO NOT break them down fast enough causing a buildup of these neurochemicals! 🧬⬆️ Some people have up to a 75% reduction in COMT enzyme activity meaning that they are only breaking down catecholamines at around 25% 😓
This sounds like a good thing… high Dopamine right?? WRONG!!
Catecholamines are structurally similar so Dopamine and Norepinephrine can readily convert into PURE ADRENALINE 😱 T